Megakaryocytes as immune cells
نویسندگان
چکیده
منابع مشابه
Platelets as immune-sensing cells.
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CD34 is expressed by essentially all human hematopoietic progenitors including cells of the megakaryocyte (MK) lineage. We have previously reported CD4 expression by some human MK (B/ood81:2,664,1993). To study the role of maturation on CD4 expression by MK, we examined CD34+ bone marrow cells for their expression of CD41 (GPllb-GPllla) and CD4 with specific monoclonal antibody (MoAbl-fluoro...
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Platelets are essential for hemostatic plug formation and thrombosis. The mechanisms of megakaryocyte (MK) differentiation and subsequent platelet production from stem cells remain only partially understood. The manufacture of megakaryocytes (MKs) and platelets from cell sources including hematopoietic stem cells and pluripotent stem cells have been highlighted for studying the platelet product...
متن کاملCharacterization of adhesive interactions between human endothelial cells and megakaryocytes.
Cell-cell adhesion is essential for many immunological functions and is believed to be important in the regulation of hematopoiesis. Adhesive interactions between human endothelial cells and megakaryocytes were characterized in vitro using the CMK megakaryocytic cell line as well as marrow megakaryocytes. Although there was no adhesion between unactivated human umbilical vein endothelial cells ...
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ژورنال
عنوان ژورنال: Journal of Leukocyte Biology
سال: 2019
ISSN: 0741-5400,1938-3673
DOI: 10.1002/jlb.mr0718-261rr